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Best practice

New Horizons addresses unmet needs in paediatric HIV care


Johnson & Johnson


A comprehensive monitoring and evaluation framework to measure the impact of the collaborative initiative New Horizons aimed at advancing paediatric HIV care.


Sub-Saharan Africa


To address the need for third-line
antiretroviral drugs in sub-Saharan Africa and to strengthen the healthcare for adolescents and children living with HIV. 


More than three million children under the age of 15 live with HIV, 90% of them in sub-Saharan Africa where only 24% are likely to receive treatment. 

In 2014, Johnson & Johnson’s pharmaceutical arm Janssen and their partners launched a collaborative initiative, New Horizons. Globally 1.8 million children under the age of 15 live with HIV. In sub-Saharan African, paediatric coverage of ART is at approximately 49%, and at the same time treatment failure is increasingly being identified.

How does this initiative improve paediatric HIV care?
Working in sub-Saharan countries with the highest burden of pediatric HIV, New Horizons aims to catalyse a collective effort to enhance access to high-quality, appropriate and sustainable treatment and care. With an integrated approach that involves donating medicines, strengthening health systems and sharing knowledge, it addresses specific needs for third-line antiretroviral treatment for children and adolescents with HIV, who are failing other treatments.

Early partners in the initiative were The Elizabeth Glaser Pediatric AIDS Foundation (EGPAF), The Partnership for Supply Chain Management (PFSCM) and Imperial Health Sciences. Others joining since 2014 include The Collaborative Initiative for Paediatric HIV Education and Research (CIPHER), The Relevance Network, and The Right to Care.

What makes this a best practice?
New Horizons’ activities to strengthen health systems include training and education for health workers, focusing on third-line treatment and psychosocial support. It addresses an unmet need for children and adolescents who are failing HIV treatment. It also addresses country-specific needs, creating tools such as dosing cards and launching an electronic education program of paediatric HIV/AIDS for healthcare workers in resource-limited settings.

Stands out for efforts to measure impact
New Horizons is recognised as a best practice because it meets all good practice standards and is also measuring its impact. EGPAF, one of its partners, is using a monitoring and evaluation (M&E) framework and logic model (‘log frame’) to guide measurements of impact.

In addition, the initiative is guided by clear goals and objectives, linked to clear measures in its M&E framework. The partnership has a governance structure with defined roles and responsibilities, and there is regular communication. Procedures are in place to mitigate risks of conflict of interest.

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